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institutional review board (IRB)

An independent committee of medical, scientific, and non-scientific members established to review, approve, and monitor research involving human participants. An institutional review board (IRB) protects the rights and welfare of human participants by assuring that a clinical trial is well designed, does not involve undue risks, and includes safeguards for participants. Any institution conducting or supporting research that involves human participants must appoint an IRB to monitor the research.

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